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If your network infrastructure consists of On-Prem Infobox appliances, you can set up the DNS Firewall service on these appliances to provide protection through RPZ (Response Policy Zones). For more information about Infoblox DNS Firewall, refer to the Infoblox NIOS Administrator Guide.
infoblox-deployment-guide-infoblox-bloxone-threat-defense-cloud-add-on-for-splunk-enterprise.pdf